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Chloroquine has been demonstrated to have activity against protozoal agents although the exact mechanism of action is not clear.

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Chloroquine may work by blocking certain enzymes or impairing the synthesis of biological molecules known as heme. There are some early reports that chloroquine might have some activity against the new coronavirus as a coronavirus treatment but there is no official indication for that use at this time, even in people who have a positive coronavirus test.

In adults, chloroquine is often prescribed as chloroquine mg once weekly equivalent to a chloroquine mg base although the exact regimen prescribed depends on the judgement of the prescribing medical provider and the health needs of the patient.

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Following oral administration, almost all of the chloroquine is absorbed from the gastrointestinal tract and the majority of the drug is found bound to proteins in the plasma. In the body, chloroquine is deposited into tissues and some excretion occurs via the urine. Additionally, some insurance plans may cover costs associated with a chloroquine phosphate prescription. People paying out of pocket should search for chloroquine coupons online to help reduce the costs associated with the medication.

One cannot just buy chloroquine online as chloroquine is a prescription medication in the United States. NBC News reported the couple believed the substance would prevent them from becoming infected with the virus. Is it effective in treating coronavirus?

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On Monday, Trump again touted chloroquine, the already-existing malaria drug that has shown effectiveness against the virus in foreign studies. Though chloroquine is approved by the Food and Drug Administration for treating malaria, lupus and rheumatoid arthritis, it has not been approved for the coronavirus. The drug can cause sudden death if a person takes 1 gram more than the recommended dosage, according to a report last week by Bloomberg News, which cited Chinese guidelines issued in February that warned health officials about the lethal side effects of the existing malaria drug chloroquine, and its derivative hydroxychloroquine.

After the virus first emerged in December, China tested the drug on about patients in clinical trials, with positive results. French physician-researchers also conducted successful clinical trial using the drug, according to The New York Post.

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But a study conducted by Wuhan Institute of Virology found that chloroquine could cause death if a person exceeds the daily recommended dosage of 1 gram. The commission recommended no more than a day course of chloroquine for adult patients at mg — half a gram — twice a day, Bloomberg reports. You should not use this medicine if you are allergic to chloroquine or hydroxychloroquine Plaquenil , or if you have:.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant. Malaria is more likely to cause death in a pregnant woman. If you are pregnant, talk with your doctor about the risks of traveling to areas where malaria is common.

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Chloroquine can pass into breast milk and may cause side effects in the nursing baby. You should not breast-feed while using this medicine. Follow all directions on your prescription label. Do not take chloroquine in larger or smaller amounts or for longer than recommended.

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To prevent malaria: Start taking the medicine 2 weeks before entering an area where malaria is common. Chloroquine is usually taken once per week on the same day each week. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. If you stop using chloroquine early for any reason, talk to your doctor about other forms of malaria prevention. To treat malaria: Chloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. To treat amebiasis: Chloroquine is given in a high starting dose for 2 days followed by a smaller dose for 2 to 3 weeks.

You may be given other medications to help prevent further infection. Take this medicine for the full prescribed length of time for treatment of malaria.

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Your symptoms may improve before the infection is completely cleared. Use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria. Call your doctor as soon as possible if you have been exposed to malaria, or if you have fever or other symptoms of illness during or after a stay in an area where malaria is common. For best results, keep using the medication as directed.

Talk with your doctor if you have fever, vomiting , or diarrhea during your treatment. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at An overdose of chloroquine can be fatal, especially in children.